Believe it or not, the Greek concept of tragedy applies to animation and cartooning. By "Greek" I mean the Homeric Greeks. According to historian Warner Yaeger the Greeks thought about tragedy differently than we do. We pity tragic heroes, they admired them.
The tragic hero led a deliberately unbalanced life. He devoted all his energy into becomming supremely good at one important thing. He may have been a lousy father and an indifferent husband, he may have had no table manners at all, but in his field of expertise he was unbeatable. Of course this skill came at a great price.
The Greeks believed that sooner or later the tragic hero would be brought down by his inability to cope with menace from the part of life that he neglected. They admired the kind of man who took this kind of risk. Modern people admire balance. The Greeks (before Aristotle's time) admired imbalance, though they thought only special people were suited for it.
How does this relate to cartooning? If you have skill and a special passion for it the Greeks say "Go for it! Go all the way and don't look back. " You'll definitely pay the price, but it's worth it.